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Some recent scientific results

  • The reuters agency reports on the results of this study : Burte E, et al. Long-term Air Pollution Exposure Is Associated With Increased Severity of Rhinitis in 2 European Cohorts. J Allergy Clin Immunol 145 (3), 834-842.e6, Mar 2020
    https://fr.reuters.com/article/healthcareSector/idUKL1N2AD1LM


  • It is increasingly evident that oxidative stress plays a role in the associations between outdoor air pollution and asthma. From 204 adult asthmatics followed in the EGEA study, the mediation analysis showed a total positive effect, a direct positive effect of O3 on persistent asthma, and an indirect positive effect mediated by plasma fluorescent oxidation products levels (FlOPs; a global and cumulative biological marker related to oxidative stress) that represented 41% of the total effect. (read more : Havet A, et al. Does the oxidative stress play a role in the associations between outdoor air pollution and persistent asthma in adults? Findings from the EGEA study. Environ Health, 18 (1), 90  2019 Oct 29)

  • The study showed that participants with higher FlOPs level at baseline had higher risk of poor asthma control eight years later. This suggests that high FlOPs level, a global oxidative stress biomarker, could be a predictor of chronic inflammatory disease evolution. (read more : Andianjafimasy M, et al. High level of fluorescent oxidation products and worsening of asthma control over time. Respir Res 2019 Sep 6;20(1):203. doi: 10.1186/s12931-019-1173-0)

 


 Complete list of references

 

Tutorials for the site EGEAnet

 Presentation of the EGEA study

 

Help to find various documents on the site of EGEAnet :

- Welcome on EGEAnet, the web site of the EGEA study

- Where can I find the "charte de confidentialité" ?

- Where can I find the composition of cooperative group EGEA ?

- Where can I find the form of access to the data ?

- Where can I find documents regarding regulatory aspects ?

- Where can I find EGEA questionnaires in public space ?