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Some recent scientific results
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While we are continually exposed to multiple environmental factors that potentially interact with each other, most previous studies have assessed the impact of a single exposure factor, or a very limited number of factors simultaneously, on health. We conducted one of the first studies based on the concept of the exposome (which represents the totality of environmental exposures) which has demonstrated a specific exposure profile associated with a lower ventilatory function in asthmatics. This exposure profile was mainly characterized by higher smoking associated with poor diet, higher outdoor humidity and greater proximity of the home to roads. These novel results reinforce the need for a more comprehensive assessment of the effects of the environment on health. (read more: Guillien A et al. Profile of exposures and lung function in adults with asthma: An exposome approach in the EGEA study. Env Res, 2020 Nov 5;110422. doi: 10.1016/j.envres.2020.110422.)
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Using a clustering approach for mixed data integrating clinical and biological characteristics, this paper identified distinct respiratory endotypes among asthmatics and never-asthmatics in adults (≥16 years old) showing different clinical characteristics at follow-up. (Read more : Nadif R, Febrissy M, Andrianjafimasy MV, et al. Endotypes identified by cluster analysis in asthmatics and non-asthmatics and their clinical characteristics at follow-up: the case-control EGEA study. BMJ Open Resp Res 2020;7:e000632. doi:10.1136/bmjresp-2020-000632)
Tutorials for the site EGEAnet
Presentation of the EGEA study
Help to find various documents on the site of EGEAnet :
- Welcome on EGEAnet, the web site of the EGEA study
- Where can I find the "charte de confidentialité" ?
- Where can I find the composition of cooperative group EGEA ?
- Where can I find the form of access to the data ?